User:Pankaj K

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Contact-new.svg Dr. Pankaj Khanna
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Employer:Acharya Narendra Dev College, University of Delhi
Occupation:Professor, Chemistry, Chemistry Department
Nationality:Indian Flag of India.svg
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About Myself

I am Prof Pankaj Khanna, teaching Organic Chemistry in the Department of Chemistry of Acharya Narendra Dev College since 2009. I love to demonstrate the beauty of chemistry of carbon to the students and synthesize new compounds for the betterment of the society. I was selected as a Vice Chancellor's fellow (University of Delhi) for the year 2014 and was recently selected as a  Digital Literacy Champion by Campus of Open Learning, University of Delhi, for further training at Edinburgh College, Scotland, UK, July 2015.

Educational qualification

I did B.Sc.(Hons) in Chemistry in 1998 from Rajdhani College and M.Sc. in Organic Chemistry from Hindu College, University of Delhi in 2000. I qualified CSIR(NET) examination held in December 1999 and have my Ph.D. in Synthetic Organic & Natural Product Chemistry with Professor S.C. Jain, Department of Chemistry, University of Delhi. I have also done a Post Graduate Diploma in Intellectual Property Rights from IGNOU.

Online Lectures

Online lectures:

  1. Stereochemistry I: The lecture deals with the concept of chirality, enantiomerism discovery, the Discovery of tetrahedral geometry of Carbon and symmetry elements.
  2. Stereochemistry II: Discussion continues to Projection formulae, Enantiomers and Diastereomers, meso compounds and Racemic mixture.
  3. Stereochemistry III: Concepts of Configuration, CIP rules and R/S configuration.
  4. Stereochemistry IV: E/Z and Resolution, then some dynamic stereochemistry which includes examples of stereoselective and stereospecific reactions, the lecture talks about.
  5. Conformations: Stereochemistry of carbon carbon single bond.
  6. Amino Acid, Peptides and Proteins: Introduction to protein, peptides and amino acids. Structure, classification and acid base behaviour of amino acids and electrophoresis.
  7. Amino Acid, Peptides and Proteins II: Methodologies for amino acids synthesis.
  8. Electronic Displacements: Basics of organic chemistry including Inductive, Electromeric, and Resonance.
  9. Electronic Displacements II: Examples of Resonance, Hyperconjugative effects and reaction mechanism.
  10. Reaction Intermediates: Starting with organic reaction intermediate, discussion on carbocation.
  11. Reaction Intermediates II: Carbanions and free radicals.
  12. Acids and Bases (with carbenes): Organic acids and bases discussed. Topic of carbenes from above (10&11) covered at the end.

Blog: Used the Blogger for flipped classroom methodology, Chemistry for Everyone

Book Chapters

  1. Leena Khanna, Mansi and Pankaj Khanna. Nanocatalysis for Reduction/Hydrogenation Reactions, Advanced Nanocatalysis for Organic Synthesis and Electroanalysis (2022) 1: 96-113. https://doi.org/10.2174/9789815040166122010008
  2. Leena Khanna, Mansi and Pankaj Khanna. Graphene Based Nanomaterials as Catalyst in Reduction Reactions, Graphene-Based Nanomaterial Catalysis (2022) 1: 130-151. https://doi.org/10.2174/9789815040494122010010
Publications
In Indexed/Peer Reviewed Journals
Year of Publication Title Journal Co-author/s

2022

Hydrotrope assisted green synthesis of dicoumarols and in silico and in vitro antibacterial, antioxidant and xanthine oxidase inhibition studies.

Journal of Biomolecular Structure and Dynamics, 2022, DOI: 10.1080/07391102.2022.2145368

Mansi, Deepshikha Gupta, Shilpa Yadav and Leena Khanna

2022

An understanding of coronavirus and exploring the molecular dynamics simulations to find promising candidates against the Mpro of nCoV to combat the COVID-19: A systematic review.

Journal of Infection and Public Health, 2022, 15(11), 1326-1349. DOI: 10.1016/j.jiph.2022.10.013

2022

A DFT Study on Diels-Alder Reaction of Dibenzazepine and 2,5-Dimethylfuran Using Different Solvents and Temperature Conditions.

Polycyclic Aromat. Compd., 2022, DOI: 10.1080/10406638.2022.2056622

Shilpa Yadav, Neeti Misra, Mansi, Kriti Batra and Leena Khanna

2021

“In water” synthesis of bis(indolyl)methanes: a review.

Synth. Commun., 2021, 51(19), 2892-2923 doi:10.1080/00397911.2021.1957113.

Leena Khanna, Mansi, Shilpa Yadav and Neeti Misra

2021

Synthesis, Comparative in vitro Antibacterial, Antioxidant & UV fluorescence studies of bis Indole Schiff bases and Molecular docking with ct-DNA & SARS-CoV-2 Mpro.

Luminescence. 2021, 36(6), 1531-1543.

Sugandha Singhal and Leena Khanna

2021

Multitarget Diallyl Disulfides (DADS) against Aβ Aggregation: Screening through Molecular Docking with Aβ42 & ZnII-Aβ16, ADME, DFT & Synthetic Strategy.

ChemistrySelect, 2021, 6(17), 4112-4123.

Sugandha Singhal, Neeti Misra and Leena Khanna.

2020

Spiro‐Indole‐Coumarin Hybrids: Synthesis, ADME, DFT, NBO Studies and In Silico Screening through Molecular Docking on DNA G‐Quadruplex

ChemistrySelect, 2020, 5(11), 3420-3433.

Leena Khanna, Sugandha Singhal and Subhash C. Jain.

2019

Recent trends in synthesis of benzimidazoles from o-phenylenediamine via nanoparticles and green strategies using transition metal catalysts.

J. Heterocyclic Chem., 2019, 56, 2702– 2729.

Sugandha Singhal and Leena Khanna.

2019

Synthesis, DFT studies, molecular docking, antimicrobial screening and UV fluorescence studies on ct-DNA for novel Schiff bases of 2-(1-aminobenzyl) benzimidazole.

Heliyon, 2019, 5, e02596. doi:10.1016/j.heliyon.2019.e02596

Sugandha Singhal and Leena Khanna.

2018

Protective effects of Aporosa octandra bark extract against D-galactose induced cognitive impairment and oxidative stress in mice.

Heliyon, 2018, 4, e00951. doi: 10.1016/j.heliyon.2018.e00951

Siva S. Panda, Adel S. Girgis, Atish Prakash, Leena Khanna, ElSayed M. Shalaby, Nehmedo G. Fawzy and Subhash C. Jain.

2018

A concise synthesis of 2-alkenyl-3-phenyl-4H-chromen-4-ones via novel C-C bond formation using sulfone as potential intermediate

Ind. J. Chem., 2018, 57B, 945-954.

Leena Khanna and Subhash C. Jain

2018

Microwave Assisted Synthesis of Spiro Heterocyclic Systems: A Review

Current Organic Chemistry, 2018, 22, 67-84.

Leena Khanna, Sean J. Thomas, Abdullah M. Asiri and Siva S. Panda

2014

Aqua mediated synthesis of spirocyclic compounds

Mini-Rev. Organic Chemistry, 11, 73-86

Siva S. Panda, Leena Khanna and Subhash C. Jain

2013

Synthesis of Various S-S Linked Symmetric Bisazaheterocycles: A Review

Mini-Rev. Organic Chemistry, 10, 268-280

Leena Khanna, Chandramukhi S. Panda and Siva S. Panda

2012

Synthetic routes to symmetric bisbenzimidazoles: a review

Mini-Rev. Org. Chem., 9, 381-396

Leena Khanna and Siva S. Panda

2012

Biginelli Reaction: A Green Perspective

Curr. Org. Chem., 16(4), 507-520

Siva S. Panda and Leena Khanna

2012

Withania somnifera reverses Alzheimer's disease pathology by enhancing low density lipoprotein receptor-related protein in liver

Proc. Natl. Acad. Sci.,109(9), 3510-3515
The Telegraph

Neha Sehgal, Alok Gupta, Rupanagudi K. Valli, Shanker D. Joshi, Jessica T. Mills, Edith Hamel, Subhash C. Jain, Suman Thakur and Vijayalakshmi Ravindranath.

2010

Withania somnifera plant extract and method of preparation thereof

PCT/IN2009/000430, Pub. No.: WO/2010/013254
Other Patents:
US Patent Granted
Australian Patent
European Patent

Vijayalaksmi Ravindranath, Alok Gupta, Neha Sehgal, Subhash C. Jain and Suman Thakur

2009

Synthesis of novel symmetrical and unsymmetrical bis-spiro[indole-indazolyl-thiazolidine]-2,4'-diones

Arkivoc, vii, 119-125

Anjali Saxena, Leena Khanna, Sunita Bhagat and Subhash C. Jain

2008 A facile synthesis of novel unsymmetrical bis-spiro[indole-pyrazolinyl-thiazolidine]-2,4'-diones Arkivoc, xv, 54-64 Manish Jain, Rajeev Sakhuja, Sunita Bhagat and Subhash C. Jain
2006 Synthesis of some novel bis-spiro[indole-pyrazolinyl-thiazolidine]-2,4'-diones   Synthetic Communications, 36, 1863-1872 Manish Jain, Anjali Saxena, Sunita Bhagat, Carl E. Olsen
2006 One pot facile synthesis of 5-alkyl-1,2-dihydro-spiro[4H-3,1-benzoxazine-2,3'[3H]indol]-4,2'-diones under microwave irradiation Indian Journal of Chemistry, 45B, 1504-1510 Anjali Saxena, Sunita Bhagat, Archana Gupta and Subhash C. Jain

2005

Novel fluorinated spiro [indole-indazolyl-thiazolidine]-2,4'-diones : Design and synthesis

Phosphorus, Sulfur, Silicon Relat Elem, 180, 1829-1839

Subhash C. Jain, Sunita Bhagat,Manish Jain and Rajeev Sakhuja
Conference  Publications
Year of Publication Title Conference Co-author/s

2010

 

Synthesis of new molecules to discover drug candidates The International Symposium on Trends in Drug Discovery and Development, 

5-8 January 2010, New Delhi, India

Subhash C. Jain et al

2008

A Clean, Benign and Aqua Mediated Synthesis of Pharamacologically Active Spiro Heterocycles

The 12th Annual Green Chemistry and Engineering Conference (June 24-26,), Washington DC 

Subhash C. Jain, Siva Panda and Sunita Bhagat


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