The Neural Crest
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Work in progress, expect frequent changes. Help and feedback is welcome. See discussion page. |
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Contents
Preknowledge, Objectives and Competencies
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In this unit we will concentrate on the neural crest, a specific group of cells that arise from the outer edges of the neural plate and migrate to form the peripheral nervous system and other tissue types. Because of their competence to form such a variety of tissue types, they are sometimes referred to as 'the fourth germ layer'. We will examine what the processes are that give rise to the neural crest, their migratory paths, and the signals that contribute to their final fate. |
At the end of this unit you should be able to:
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Activities and Reading Material
| During class, we will look at the process by which the neural crest cells are formed. Using the diagrams provided we will examine the migration paths of the different populations of neural crest cells and how they relate to their final fate. We will identify the signalling mechanisms that guide and determine the final differentiation of neural crest cells into their derivatives. We will also examine the experimental approaches that have allowed the study of neural crest differentiation.
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- Jacobsen Chapter 4
Assignments
| After class, you are expected to review your notes and use the assigned reading material to contribute to the questions and definitions sections below. Please use the discussion page if you want to discuss any particular topic on the material. You are also welcome to add links to videos or audio files in the Media box or links to online resources in the Web Resources box below. |
Questions
| How are the neural crest cells specified? |
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| Describe the different migration paths of the spinal cord neural crest and the different structures they give rise to. |
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| Describe the different migration paths of the cranial neural crest and the strictures they will become a part of. |
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Definitions
You should be able to provide a comprehensive functional and structural definition for the terms associated with this topic:
(Sclerotome, myotome, somites, parasympathetic nervous system, sympathetic nervous system. pharyngeal arches).
| Sclerotome: |
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| Myotome: |
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| Somite: |
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| Parasympathetic Nervous System: |
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| Sympathetic Nervous System: |
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| Pharyngeal Arches: |
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Additional study material
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Related Content
Go back to the introductory page, return to Unit 4: Pattern Formation, Antero-Posterior (AP) and Dorso-Ventral (DV) Axes Formation, or continue with Unit 6: The Ectodermal Placodes.
