Thread:Biological Clock 1 (1)

Preface What is Bio-velocity?

To discuss biological clock, first, the fact that because of existence of a velocity, body temperature keep at constant has to be recognized and even in bedridden condition, velocity exists. To understand velocity in bedridden condition, nutrients have to be given to support for the movements of at least the heart, lung and other internal organs to live. These muscle activities can be converted into velocity from the amount of nutrients called basic metabolic rate using the equation of motion as below. $$w=mv2/2$$ Note that calorie multiplied by 4.18 is joules which is the same unit of work done in thermodynamics. Work done is assumed to be 1% of basic metabolic rate. Formula for basic metabolic rate for man and woman are as follows basic metabolic rate for man = 66 + (13.7 x body weight in kg) + (5 x hight in cm) - (6.7 x age year) basic metabolic rate for woman =665 + (9.6 x body weight in kg) + (1.7 x hight in cm) - (7 x age year) The formula of basic velocity is given below. a: basic metabolic rate, bw: body weight, SQRT: SQUER ROOT v (km/h)=0.36 x SQRT(a/10bw) Now velocity even in bedridden condition no doubt does really exist.

Velocity of active movements such as walking and running is measured using stepper. Suppose 10,000 steps walk in a day was done, 1 step width is 0.5m, 5km per 24 hours, then average velocity of active movements in a day is 0.21km/h. This velocity is called acitive velocity.

The sum of basic and active velocities is named bio-velocity.

In the next chapter, I would like to show velocity change by age in mouse as well as in human. In mouse, velocity was calculated from the free heat measurements, in human velocity was calculated from the above formula.